New organisms included upon user request New analysis suggestions and explanations as help button included
CLUEGO CYTOSCAPE VISUALIZATION NETWORK UPDATE
Improved network update behavior and speed Additional iterative merging of functional groups for large networks
InterPro download was not working due to a change of the source data link In certain graphic card driver versions a stricter usage of data types is needed Overlapping terms were included more than once in a group Percentage of not found genes are now reported to unique genes, not to the initial uploaded ids Correction of the stats displayed in the ClueGO log. ClueGO functions are now REST enabled, and allow the integration of ClueGO in analytical pipelines. To extend it's functionality get as well CluePedia.ĬlueGO visualizes also terms and pathways resulted from other enrichment analyses as functionally grouped networks.Ĭytoscape Automation enables scientific workflows written in many languages through the CyREST. ClueGO is easy updatable with the newest files from Gene Ontology, KEGG, WikiPathways and Reactome. The significance of the terms and groups is automatically calculated. ClueGO charts are underlying the specificity and the common aspects of the biological role. On the network, the node colour can be switched between functional groups and clusters distribution. The ClueGO network is created with kappa statistics and reflects the relationships between the terms based on the similarity of their associated genes. The related terms which share similar associated genes can be fused to reduce redundancy. From the ontology sources used, the terms are selected by different filter criteria. ClueGO performs single cluster analysis and comparison of several clusters (lists of genes). The type of identifiers supported can be easily extended by the user. The identifiers can be uploaded from a text file or interactively from a network of Cytoscape. ClueGO is a Cytoscape plug-in that visualizes the non-redundant biological terms for large clusters of genes in a functionally grouped network.
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